Children's Hospital Los Angeles

E-protocol Insulin - Objective and Study Design
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Background:


The focus of this study is a software decision-support tool (eProtocol-insulin) developed to guide caretakers in insulin administration. The eProtocol-insulin software will be housed in laptop computers placed at the bedside or in a location close to patients' rooms.


Objectives of the study:


We will implement the validated Phase-1 eProtocol-insulin with the 80-110 mg/dl target in both adult and pediatric Phase-2 (naive) sites.
     a. We will calculate clinician compliance with eProtocol-insulin instructions.
               i. We will quantify the reasons for non-compliance with protocol instructions.
     b. Regarding the 80-110 mg/dl blood glucose target, we will calculate:
              i. The proportion of measurements between 80-110 mg/dl for:
                  a. All measurements
                  b. Measurements after first reaching 80-110 mg/dl.
              ii. The time required to first reach 80-110 mg/dl.
     c. We will repeat the calculations for i.b above for glucose values falling within the    
         normal range (between 70 and 110 mg/dl).